The Portuguese winger's two second-half goals ended Everton's unbeaten run and secured Chelsea's first Premier League clean sheet in nine months, though the result was overshadowed by a serious head injury to goalkeeper Emiliano Martinez.
Pep Chavarria is absent despite travelling to the Hill Dickinson Stadium, while Reece James begins rehabilitation after successful knee surgery.
The England midfielder has rejected contract offers at Bournemouth and the Cherries are now open to selling him in January if their price is met and Premier League survival looks secure.
Two sides level on three points meet at Parc Olympique Lyonnais on Thursday as Lyon host Crystal Palace in the UEFA Europa League League Stage.
