Fulham, rooted in the bottom two with just two points from six matches, host a Hull City side sitting comfortably mid-table in the Premier League.
The Arsenal manager says reducing up to 60 roles is necessary to keep the club moving forward, but the timing alongside his own new contract has drawn scrutiny.
Second-half goals from Timber, Eze and Saka swept Arsenal past a stubborn Lille side who had kept them at bay for an hour.