Beşiktaş carry a one-goal advantage and a three-match winning run into Thursday's second leg at Besiktas Park.
Manchester City have confirmed the signing of Argentine goalkeeper Gerónimo Rulli from Marseille on a two-year deal worth up to €2 million, with the 34-year-old returning to the Etihad Stadium to serve as back-up to number one Gianluigi Donnarumma.